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Glucosamine is a naturally occurring, essential component of glycosaminoglycans, sponge-like compounds which absorb and bind water within cartilage.  Glucosamine hydrochloride is thought crucial for helping to maintain joint cushioning, flexibility, function, and integrity.  Glucosamine hydrochloride is also thought to be important in the formation and structure of bones, tendons, ligaments, and other connective tissue, stimulating cartilage production, natural joint repair, and reduction of joint inflammation. MSM (methylsulfonymethane) is a naturally occurring sulfur compound and a derivative of DSMO, it supports the integrity of healthy mucous membranes, and is necessary for the production of collagen and keratin, the primary proteins in hair, skin, and nails.  MSM also plays an essential role in the formation of bones, joints, ligaments, and tendons. MSM is primarily used for its natural and remarkable anti-inflammatory properties, which are especially useful in alleviating pain, joint inflammation, muscle spasms, allergies, and gastrointestinal inflammation.  Its maintenance of healthy cell membranes may help to prevent allergies and support normal lung function. Collagen is the major structural component of articular cartilage in joints. Type II collagen from chicken sternal cartilage contains the highest amount of anti-inflammatory and joint-related proteoglycans. It is also much more absorbable than other forms of collagen, with an absorption rate of 70 to 90 percent. It supports production of synovial fluid, decreases levels inflammatory cytokines and increases T-suppressor cells.   Enzymes are included in the product to enhance absorption of the glucosamine and chondroitin molecules.